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Electrowetting on Dielectric (view source)
Revision as of 06:47, 14 September 2017
, 06:47, 14 September 2017no edit summary
==DNA Synthesizer==
==DNA Synthesizer==
SSI Biology will use an EWOD-based system in their [[DNA Synthesizer]]. The growing DNA strands will be immobilized on magnetic beads in a droplet on one electrode. Droplets containing DNA synthesis reagents like [[Terminal Deoxynucleotidyl Transferase]] can be merged with the droplet containing the DNA to start reactions. When a given reaction step is complete, the droplet can then be moved off the electrode containing the DNA to a waste chamber, without the magnetic bead-bound DNA being washed away. After the desired DNA sequence is synthesized, it can be cleaved off the beads and moved to a desired location for downstream applications.
SSI Biology will use an EWOD-based system in their [[DNA Synthesizer]]. The growing DNA strands will be immobilized on magnetic beads in a droplet on one electrode. Droplets containing DNA synthesis reagents like [[Terminal Deoxynucleotidyl Transferase]] can be merged with the droplet containing the DNA to start reactions. When a given reaction step is complete, the droplet can then be moved off the electrode containing the DNA to a waste chamber, without the magnetic bead-bound DNA being washed away. After the desired DNA sequence is synthesized, it can be cleaved off the beads and moved to a desired location for downstream applications.
[[Category:Biology]]