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Biology Team's Pilot Project
Biology Team's Pilot Project
==Biology Team's 2016 Pilot Project==
==SSI Bio 2016 Pilot Project==
SSI Bio is launching with the DNA synthesizer as their primary project.
==Components of the Synthesis Project==
==Components of the Synthesis Project==
SSI Bio will be breaking up this DNA synthesizer project into several smaller subteams to tackle the several different systems needed
===Enzymatic Synthesis Chemistry===
===Safe Phosphoramidite Chemistry===
===Safe Phosphoramidite Chemistry===
A more conventional alternative to aiming for enzymatic synthesis would be to try to adjust conventional phosphoramidite chemistry to be safer for use in space. This might involve creating a system that can synthesize DNA using safer organic solvents and less toxic reagents.
===Microfluidic Synthesizer Design===
===Microfluidic Synthesizer Design===
===Reassembly Chemistry and Algorithm===
===Reassembly Chemistry and Algorithm===
====Overview====
====Overview====
Once a strand of DNA is made, we will need to check to make sure that it is the correct desired sequence.
Once a strand of DNA is made, we will need to check to make sure that it is the correct desired sequence.
==Effects of limits of Space on Synthesizer==
===Payload Size and Power constraints===
We'd like to fit our synthesizer into a 10 centimeter cube, so that it could be launched on a [https://en.wikipedia.org/wiki/CubeSat CubeSat] or other standardized research payload.
===What kind of shielding do we need?===
We're not sure what kind of shielding we need! UV radiation can have damage DNA through a process called [https://en.wikipedia.org/wiki/Direct_DNA_damage Direct DNA damage] that can lead to thymine or pyrimidine dimers. This is what causes sunburn, and it's why your skin can tan to help block out UVB.
====Communication from Device====
====Communication from Device====